Matoug-Elwerfelli, M, Nazzal, H, Duggal, M et al. (1 more author) (2021) What the future holds for regenerative endodontics: novel antimicrobials and regenerative strategies. European Cells and Materials, 41. pp. 811-833. ISSN 1473-2262
Abstract
Regenerative/revitalisation endodontic techniques are increasingly used as a treatment approach for the management of immature permanent teeth with necrotic pulps. Different chemical irrigants and medicaments are routinely used clinically for intra-canal disinfection. However, despite remarkable progress in this field, coronal discolouration, cell cytotoxicity, difficulty of removal of organic biofilm from the root canal, development of sensitisation and antimicrobial resistance are still challenges to this line of treatment. This review critically discusses and challenges the current status quo of antimicrobials used in regenerative endodontics and sheds the light on future alternative antimicrobial materials with regenerative potential.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Authors. This is an open access article under the terms of the Creative Commons Attribution-ShareAlike 4.0 International license (CC BY-SA 4.0). |
Keywords: | Antimicrobials, antibiotics, disinfection, biomaterials, regenerative endodontics, drug delivery, dental pulp stem cells, pulp regeneration |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Dentistry (Leeds) > Oral Biology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 15 Nov 2021 13:16 |
Last Modified: | 25 Jun 2023 22:49 |
Status: | Published |
Publisher: | AO Research Institute Davos |
Identification Number: | 10.22203/ecm.v041a51 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:180351 |