Mills, C orcid.org/0000-0002-3436-3876, Jones, R and Huckabee, M-L (2017) Measuring voluntary and reflexive cough strength in healthy individuals. Respiratory Medicine, 132. pp. 95-101. ISSN 0954-6111
Abstract
Background
Cough reflex testing is a validated tool for identifying patients at risk of silent aspiration. However, inter- and intra-rater reliabilities of perceptual judgements of cough strength are sub-optimal. Although there are clinically established methods for measuring volitional cough strength, no similar methods are identified for reflexive cough strength. This study evaluated three measurement methods of voluntary and suppressed reflexive cough strength.
Methods
Fifty-three healthy subjects (≥50 years) participated in this study. Participants produced ‘strong’ and ‘weak’ voluntary coughs and suppressed reflexive coughs to incremental doses of citric acid. Peak and area under the curve (AUC) measurements were taken of pressure, airflow, and acoustics.
Results
There was no dose effect of citric acid on measures of reflexive cough strength. Strong voluntary coughs were stronger than reflexive coughs for all measures (p < 0.001) and weak voluntary coughs were stronger than reflexive coughs for two measures (AUC pressure: p < 0.020; peak flow: p < 0.004). AUC pressure and peak flow had the highest correlations and effect sizes. Correlations were low between voluntary and reflexive cough strength for all measures (r ≤ 0.46).
Conclusion
Assessing strength of reflexive cough, rather than voluntary cough, is highly desirable in the dysphagic population. Pressure and flow provide the most useful objective measurements.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Keywords: | Reflexive cough; Voluntary cough; Cough strength; Pressure; Airflow; Acoustic |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 11 Nov 2021 16:39 |
Last Modified: | 11 Nov 2021 16:39 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.rmed.2017.09.013 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:180215 |