John, M Joseph, Kuriakose, Philip, Smith, Mark et al. (2 more authors) (2021) The long shadow of socioeconomic deprivation over the modern management of acute myeloid leukemia: time to unravel the challenges:time to unravel the challenges. Blood Cancer Journal. 141. pp. 1-8. ISSN 2044-5385
Abstract
Biological and non-biological variables unrelated to acute myeloid leukemia (AML) preclude standard therapy in many settings, with "real world" patients under-represented in clinical trials and prognostic models. Here, using a case-based format, we illustrate the impact that socioeconomic and anthropogeographical constraints can have on optimally managing AML in 4 different healthcare systems. The granular details provided, emphasize the need for the development and targeting of socioeconomic interventions that are commensurate with the changing landscape of AML therapeutics, in order to avoid worsening the disparity in outcomes between patients with biologically similar disease.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © The Author(s) 2021 |
Keywords: | Adult,Aged,Delivery of Health Care,Disease Management,Humans,Leukemia, Myeloid, Acute/diagnosis,Male,Middle Aged,Prognosis,Socioeconomic Factors |
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Health Sciences (York) |
Depositing User: | Pure (York) |
Date Deposited: | 22 Oct 2021 08:40 |
Last Modified: | 16 Oct 2024 17:56 |
Published Version: | https://doi.org/10.1038/s41408-021-00533-0 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1038/s41408-021-00533-0 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:179498 |