Kakonyi, G., Mulligan, S., Fairburn, A.W. et al. (5 more authors) (2021) Simultaneous detection of monomers associated with resin-based dental composites using SPME and HPLC. Dental Materials Journal, 40 (4). pp. 1007-1013. ISSN 0287-4547
Abstract
As resin-based composites (RBC) replace dental amalgam for environmental reasons, there is a requirement to understand the environmental impact of this alternative dental restorative material. In this study we standardize the simultaneous detection of five monomeric components associated with RBCs using high performance liquid chromatography (HPLC) coupled with solid-phase microextraction (SPME). Factors affecting method performance (detection wavelength, calibration conditions, method sensitivity/accuracy/precision, extraction time/efficiency) are evaluated using standard solutions containing the mixture of TEGDMA, UDMA, Bis-GMA, BPA and HEMA. Detection sensitivity and analytical efficiency of the method is optimized for these compounds using 200 nm detection wavelength, PDMS/DVB fiber and extraction time of 90 min. Analytical accuracy of the HPLC is >95% for all monomers, with precision of 2.3–5.1%. Detection limits under the conditions described are 25 µg/L for HEMA, BPA, UDMA, Bis-GMA, and 100 µg/L for TEGDMA. The extraction time is governed by the largest molecular weight compounds.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2021 The Japanese Society for Dental Materials and Devices. |
Keywords: | Dental restoration; Resin-based composite; Plastic pollution; HPLC; SPME |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Civil and Structural Engineering (Sheffield) The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Clinical Dentistry (Sheffield) |
Funding Information: | Funder Grant number BRITISH DENTAL ASSOCIATION 002-2013 BRITISH DENTAL ASSOCIATION 002-2013 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 01 Oct 2021 11:31 |
Last Modified: | 14 Oct 2021 11:36 |
Status: | Published |
Publisher: | Japanese Society for Dental Materials and Devices |
Refereed: | Yes |
Identification Number: | 10.4012/dmj.2020-240 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:178657 |