Coleman, Tim, Clark, Miranda, Welch, Charlie orcid.org/0000-0002-2421-5538 et al. (11 more authors) (2022) Effectiveness of offering tailored text message, self-help smoking cessation support to pregnant women who want information on stopping smoking:MiQuit3 randomised controlled trial and meta-analysis. Addiction. pp. 1079-1094. ISSN 1360-0443
Abstract
Aims To test efficacy of “MiQuit’, a tailored, self-help, text message stop smoking programme for pregnancy, as an adjunct to usual care (UC) for smoking cessation in pregnancy. Design Multicentre, open, two-arm, parallel-group, superiority randomised controlled trial (RCT) and a Trial Sequential Analysis (TSA) meta-analysis combining trial findings with two previous ones. Setting 24 English hospital antenatal clinics. Participants 1002 pregnant women who were ≥16 years old, were ≤ 25 weeks gestation, and smoked ≥ one daily cigarette and accepted information on cessation with no requirement to set quit dates. Interventions UC or UC plus ‘MiQuit’: 12 weeks of tailored, smoking cessation text messages focussed on inducing and aiding cessation. Measurements Primary outcome: biochemically-validated cessation between 4 weeks after randomisation and late pregnancy. Secondary outcomes: shorter and non-validated abstinence periods, pregnancy outcomes and incremental cost-effectiveness ratios. Findings RCT: cessation was 5.19% (26/501) and 4.59% (23/501) in MiQuit and UC groups [adjusted odds ratio (adj OR) for quitting with MiQuit versus UC, 95% confidence interval (CI), 1.15 (0.65 to 2.04)]; other abstinence findings were similar, with higher point estimates. Primary outcome ascertainment was 61.7% (309) and 67.3% (337) in MiQuit and UC groups with 71.1% (54/76) and 69.5% (41/59) abstinence validation rates, respectively. Pregnancy outcomes were similar and the incremental cost per Quality-Adjusted Life Year was -£1,118 (95% CI -£4,806 to £1,911). More MiQuit group women reported making at least one quit attempt (adj OR (95% CI) for making an attempt, 1.50 (1.07 to 2.09). TSA Meta-analysis: This found no significant difference in prolonged abstinence between MiQuit and UC (pooled OR 1.49, adjusted 95% CI 0.62 to 3.60). Conclusions Irrespective of whether they want to try quitting, when offered a tailored, self-help, text message stop smoking programme for pregnancy (MiQuit) as an adjunct to usual care, pregnant women are not more likely to stop smoking until childbirth but they report more attempts at stopping smoking.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2021 The Authors |
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Health Sciences (York) |
Funding Information: | Funder Grant number CANCER RESEARCH UK UNSPECIFIED |
Depositing User: | Pure (York) |
Date Deposited: | 30 Sep 2021 09:20 |
Last Modified: | 16 Oct 2024 17:53 |
Published Version: | https://doi.org/10.1111/add.15715 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1111/add.15715 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:178639 |
Download
Filename: add.15715.pdf
Description: Effectiveness of offering tailored text message, self-helpsmoking cessation support to pregnant women who wantinformation on stopping smoking: MiQuit3 randomisedcontrolled trial and meta-analysis
Licence: CC-BY 2.5