Kumar, P. orcid.org/0000-0002-9965-8691, Ebbens, S. orcid.org/0000-0002-4727-4426 and Zhao, X. orcid.org/0000-0002-4620-2893 (2021) Inkjet printing of mammalian cells – Theory and applications. Bioprinting, 23. e00157. ISSN 2405-8866
Abstract
Inkjet bioprinting is a new and versatile technology which has found novel applications in cell biology and associated biomedical research. Cells suspended in a low-viscosity liquid medium can be readily dispensed using piezoelectric and thermal actuation-based drop-on-demand inkjet printers, which are the most commonly used inkjet printing technologies. As inkjet printing has the advantage of producing high resolution and high precision prints, it is one of the most suitable technologies for bottom-up cell deposition for building intricate biological constructs. In addition, with the use of appropriate bioinks, inkjet printing can produce both, 2D as well as 3D structures. This review paper is an attempt to curate inkjet bioprinting research, with an exclusive focus on mammalian cells, and comprehend the main application areas, such as intracellular delivery and transfection, gene expression modification, single cell sorting, cell microarray, cell micropatterning, tissue engineering, and in vivo cell printing. The printability of cells has also been discussed in order to understand how the process of inkjet bioprinting affects the cellular mechanics and physiology and subsequent survival, proliferation and differentiation.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2021 The Authors. Published by Elsevier B.V. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
Keywords: | Inkjet bioprinting; Cell printing; Transfection; Gene expression; Microarray; Micropatterning; Tissue engineering; In vivo bioprinting |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Chemical and Biological Engineering (Sheffield) |
Funding Information: | Funder Grant number ENGINEERING AND PHYSICAL SCIENCE RESEARCH COUNCIL EP/J002402/1 ENGINEERING AND PHYSICAL SCIENCE RESEARCH COUNCIL EP/N033736/1 Engineering and Physical Sciences Research Council EP/N023579/1 Engineering and Physical Sciences Research Council EP/N007174/1 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 22 Sep 2021 14:07 |
Last Modified: | 28 Sep 2021 09:04 |
Status: | Published |
Publisher: | Elsevier BV |
Refereed: | Yes |
Identification Number: | 10.1016/j.bprint.2021.e00157 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:178420 |