Mendes, AC, Shekarforoush, E, Engwer, C et al. (4 more authors) (2016) Co-assembly of chitosan and phospholipids into hybrid hydrogels. In: Pure and Applied Chemistry. 12th Conference of the European Chitin Society (12th EUCHIS)/13th International Conference on Chitin and Chitosan (13th ICCC), 30 Aug - 02 Sep 2015, Münster, Germany. De Gruyter , pp. 905-916.
Abstract
Novel hybrid hydrogels were formed by adding chitosan (Ch) to phospholipids (P) self-assembled particles in lactic acid. The effect of the phospholipid concentration on the hydrogel properties was investigated and was observed to affect the rate of hydrogel formation and viscoelastic properties. A lower concentration of phospholipids (0.5% wt/v) in the mixture, facilitates faster network formation as observed by Dynamic Light Scattering, with lower elastic modulus than the hydrogels formed with higher phospholipid content. The nano-porous structure of Ch/P hydrogels, with a diameter of 260±20 nm, as observed by cryo-scanning electron microscopy, facilitated the penetration of water and swelling. Cell studies revealed suitable biocompatibility of the Ch/P hydrogels that can be used within life sciences applications.
Metadata
Item Type: | Proceedings Paper |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | ©2016 IUPAC & De Gruyter. This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. For more information, please visit: http://creativecommons.org/licenses/by-nc-nd/4.0/. |
Keywords: | biomaterials; carbohydrates; chitosan; colloids; EUCHIS-12; hydrogel; ICCC-13; phospholipids; self-assembly |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Environment (Leeds) > School of Food Science and Nutrition (Leeds) > FSN Chemistry and Biochemistry (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 23 Aug 2021 09:15 |
Last Modified: | 23 Aug 2021 09:15 |
Status: | Published |
Publisher: | De Gruyter |
Identification Number: | 10.1515/pac-2016-0708 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:177307 |