COVID-19 in children with haematological malignancies

Abstract

Background

Children with cancer are not at increased risk of severe SARS-CoV-2 infection; however, adults with haematological malignancies have increased risk of severe infections compared with non-haematological malignancies.

Methods

We compared patients with haematological and non-haematological malignancies enrolled in the UK Paediatric Coronavirus Cancer Monitoring Project between 12 March 2020 and 16 February 2021. Children who received stem cell transplantation were excluded.

Results

Only 2/62 patients with haematological malignancy had severe/critical infections, with an OR of 0.5 for patients with haematological compared with non-haematological malignancies.

Interpretation

Children with haematological malignancies are at no greater risk of severe SARS-CoV-2 infection than those with non-haematological malignancies.

Metadata

Item Type:	Article
Authors/Creators:	Millen, GC Arnold, R Cazier, J-B Curley, H Feltbower, R https://orcid.org/0000-0002-1728-9408 Gamble, A Glaser, A https://orcid.org/0000-0003-1814-5120 Grundy, RG Kirton, L Lee, LYW McCabe, MG Palles, C Phillips, B Stiller, CA Varnai, C Kearns, P
Copyright, Publisher and Additional Information:	© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY. Published by BMJ. This is an open access article distributed in accordance with the Creative Commons Attribution 4.0 Unported (CC BY 4.0) license, which permits others to copy, redistribute, remix, transform and build upon this work for any purpose, provided the original work is properly cited, a link to the licence is given, and indication of whether changes were made.
Keywords:	COVID-19; data collection; epidemiology
Dates:	Published: February 2022 Published (online): 22 July 2021
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Clinical & Population Science Dept (Leeds)
Depositing User:	Symplectic Publications
Date Deposited:	03 Aug 2021 09:59
Last Modified:	25 Jun 2023 22:43
Status:	Published
Publisher:	BMJ Publishing Group
Identification Number:	10.1136/archdischild-2021-322062
Related URLs:	PubMed URL
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:176746

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COVID-19 in children with haematological malignancies

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