Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores

Abstract

Objective

To perform region-based development of whole-body MRI through validation of knee region scoring systems in spondyloarthritis (SpA).

Methods

Assessment of knee inflammatory pathologies using 2 systems, OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses (MRI-WIPE) and Knee Inflammation MRI Scoring System (KIMRISS), in 4 iterative multi-reader exercises.

Results

In the final exercise, reliability was mostly good for readers with highest agreement in previous exercise. Median pairwise single-measure ICCs for osteitis and synovitis/effusion status/change were 0.71/0.48 (WIPE-osteitis), 0.48/0.77 (WIPE-synovitis/effusion), 0.59/0.91 (KIMRISS-osteitis) and 0.92/0.97 (KIMRISS-synovitis/effusion). SRMs were 0.74 (WIPE-synovitis/effusion) and 0.78 (KIMRISS-synovitis/effusion).

Conclusion

MRI-WIPE and KIMRISS may both be useful in SpA whole-body evaluation studies.

Metadata

Item Type:	Article
Authors/Creators:	Wetterslev, M Maksymowych, WP Lambert, RGW Eshed, I Pedersen, SJ Stoenoiu, MS Krabbe, S Bird, P Foltz, V Mathew, AJ Gandjbakhch, F Paschke, J Carron, P De Marco, G https://orcid.org/0000-0003-2406-161X Marzo-Ortega, H Poulsen, AEF Jaremko, JL Conaghan, P https://orcid.org/0000-0002-3478-5665 Østergaard, M
Copyright, Publisher and Additional Information:	© 2021 Elsevier Inc. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY 4.0), which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.
Keywords:	OMERACT; Spondyloarthritis; Knee; Whole-body MRI; MRI-WIPE; KIMRISS
Dates:	Published: August 2021 Published (online): 17 June 2021 Accepted: 4 June 2021
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Musculoskeletal Medicine & Imaging (Leeds)
Depositing User:	Symplectic Publications
Date Deposited:	09 Jun 2021 11:20
Last Modified:	30 May 2023 22:37
Status:	Published
Publisher:	Elsevier
Identification Number:	10.1016/j.semarthrit.2021.05.013
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:175033

CORE (COnnecting REpositories)

Joint and entheseal inflammation in the knee region in spondyloarthritis - reliability and responsiveness of two OMERACT whole-body MRI scores

Abstract

Metadata

Download

Published Version

Export

Statistics