Arthritis and enthesitis in the hip and pelvis region in spondyloarthritis – OMERACT validation of two whole-body MRI methods

Abstract

Objective

: To validate reliability, correlation and responsiveness of two whole-body MRI scores for the hip/pelvis region in spondyloarthritis.

Methods

: Assessment of hip/pelvis inflammation in 4 multi-reader exercises using the OMERACT MRI Whole-body score for Inflammation in Peripheral joints and Entheses(MRI-WIPE) and Hip Inflammation Magnetic Resonance Imaging Scoring System(HIMRISS).

Results

: In exercises 3-4 (11/20 cases, respectively; 9 readers) reliability was mostly good for the 3 best calibrated readers. Median pairwise single-measure ICC for status were 0.58-0.65(WIPE-osteitis), 0.10-0.88(HIMRISS-osteitis) and for status/change 0.38-0.72/0.52-0.60(WIPE-synovitis/effusion) and 0.68-0.89/0.78-0.85(HIMRISS-synovitis/effusion). SRM was 1.23 for WIPE-osteitis, while lower for WIPE-synovitis/effusion and HIMRISS.

Conclusion

: MRI-WIPE and HIMRISS may after further validation be useful in future spondyloarthritis trials.

Metadata

Item Type:	Article
Authors/Creators:	Wetterslev, M Lambert, RGW Maksymowych, WP Eshed, I Pedersen, SJ Bird, P Stoenoiu, MS Krabbe, S Mathew, AJ Foltz, V Gandjbakhch, F Paschke, J De Marco, G https://orcid.org/0000-0003-2406-161X Marzo-Ortega, H Carron, P Poulsen, AEF Jaremko, JL Conaghan, PG https://orcid.org/0000-0002-3478-5665 Østergaard, M
Copyright, Publisher and Additional Information:	©2021 Published by Elsevier Inc. This is an author produced version of an article, published in Seminars in Arthritis and Rheumatism. Uploaded in accordance with the publisher's self-archiving policy.
Keywords:	OMERACT; Spondyloarthritis; Hip; Whole-body MRI; MRI-WIPE; HIMRISS
Dates:	Published: August 2021 Published (online): 21 May 2021 Accepted: 14 May 2021
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Musculoskeletal Medicine & Imaging (Leeds)
Depositing User:	Symplectic Publications
Date Deposited:	25 May 2021 09:04
Last Modified:	12 Jul 2022 14:32
Status:	Published
Publisher:	Elsevier
Identification Number:	10.1016/j.semarthrit.2021.05.006
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:174307

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Arthritis and enthesitis in the hip and pelvis region in spondyloarthritis – OMERACT validation of two whole-body MRI methods

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