Tickner, Ben J., Stasiuk, Graeme J., Duckett, Simon B. orcid.org/0000-0002-9788-6615 et al. (1 more author) (2020) The use of yttrium in medical imaging and therapy:historical background and future perspectives. Chemical Society Reviews. pp. 6169-6185. ISSN 0306-0012
Abstract
Yttrium is a chemically versatile rare earth element that finds use in a range of applications including lasers and superconductors. In medicine, yttrium-based materials are used in medical lasers and biomedical implants. This is extended through the array of available yttrium isotopes to enable roles for 90Y complexes as radiopharmaceuticals and 86Y tracers for positron emission tomography (PET) imaging. The naturally abundant isotope 89Y is proving to be suitable for nuclear magnetic resonance investigations, where initial reports in the emerging field of hyperpolarised magnetic resonance imaging (MRI) are promising. In this review we explore the coordination and radiochemical properties of yttrium, and its role in drugs for radiotherapy, PET imaging agents and perspectives for applications in hyperpolarised MRI. This journal is
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Royal Society of Chemistry 2020. Funding Information: We would like to thank Prof. Simon Cotton for help in obtaining the literature on lanthanide and actinide chemistry and Prof. Gyula Tirsco for helpful discussions on kinetic inertness. B. J. T. would like to thank the Wild Overseas Scholar’s Fund (University of York) for financial support. G. J. S. would like to thank the MRC for funding (MR/T002573/1). Open Access funding provided by the Max Planck Society. |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 12 Mar 2021 11:10 |
Last Modified: | 16 Oct 2024 17:25 |
Published Version: | https://doi.org/10.1039/c9cs00840c |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1039/c9cs00840c |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:172130 |
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Description: The use of yttrium in medical imaging and therapy: historical background and future perspectives
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