Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI

Kearney, KJ orcid.org/0000-0002-0387-6812, Butler, J, Posada, OM et al. (10 more authors) (2021) Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI. Proceedings of the National Academy of Sciences, 118 (3). e201481011. ISSN 0027-8424

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Item Type: Article
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Copyright, Publisher and Additional Information:

© 2021 the Author(s). Published by PNAS. This open access article is distributed under Creative Commons Attribution License 4.0 (CC BY).

Keywords: plasma kallikrein; prekallikrein; Factor IX; intrinsic pathway; Factor XII
Dates:
  • Published (online): 4 January 2021
  • Published: 19 January 2021
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 02 Feb 2021 13:58
Last Modified: 02 Feb 2021 13:58
Status: Published
Publisher: Proceedings of the National Academy of Sciences
Identification Number: 10.1073/pnas.2014810118
Open Archives Initiative ID (OAI ID):

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