Fenton, HM orcid.org/0000-0001-7824-2614, Finan, PJ, Milton, R et al. (4 more authors) (2020) National variation in pulmonary metastasectomy for colorectal cancer. Colorectal Disease. ISSN 1462-8910
Abstract
Aim
Evidence on patterns of use of pulmonary metastasectomy in colorectal cancer patients is limited. This population‐based study aims to investigate the use of pulmonary metastasectomy in the colorectal cancer population across the English National Health Service (NHS) and quantify the extent of any variations in practice and outcome.
Methods
All adults who underwent a major resection for colorectal cancer in an NHS hospital between 2005 and 2013 were identified in the COloRECTal cancer data Repository (CORECT‐R). All inpatient episodes corresponding to pulmonary metastasectomy, occurring within 3 years of the initial colorectal resection, were identified. Multi‐level logistic regression was used to determine patient and organizational factors associated with the use of pulmonary metastasectomy for colorectal cancer, and Kaplan–Meier and Cox models were used to assess survival following pulmonary metastasectomy.
Results
In all, 173 354 individuals had a major colorectal resection over the study period, with 3434 (2.0%) undergoing pulmonary resection within 3 years. The frequency of pulmonary metastasectomy increased from 1.2% of patients undergoing major colorectal resection in 2005 to 2.3% in 2013. Significant variation was observed across hospital providers in the risk‐adjusted rates of pulmonary metastasectomy (0.0%–6.8% of patients). Overall 5‐year survival following pulmonary resection was 50.8%, with 30‐day and 90‐day mortality of 0.6% and 1.2% respectively.
Conclusions
This study shows significant variation in the rates of pulmonary metastasectomy for colorectal cancer across the English NHS.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2021 The Authors. This is an open access article under the terms of the Creative Commons Attribution 4.0 International License (CC BY 4.0) (https://creativecommons.org/licenses/by/4.0/) |
Keywords: | colorectal cancer, pulmonary metastasectomy, pulmonary metastases |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Inst of Biomed & Clin Sciences (LIBACS) (Leeds) > Trans Anaesthetics & Surgical Sciences (Leeds) |
Funding Information: | Funder Grant number Yorkshire Cancer Research L394 Cancer Research UK C23434/A23706 |
Depositing User: | Symplectic Publications |
Date Deposited: | 08 Dec 2020 11:22 |
Last Modified: | 25 Jun 2023 22:31 |
Status: | Published online |
Publisher: | Wiley |
Identification Number: | 10.1111/codi.15506 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:168763 |