Guardians of the genome: DNA damage and repair

Abstract

This collection of reviews aims to summarise our current understanding of a fundamental question: how do we deal with DNA damage? After identifying key players that are important for this process, we are now starting to reveal the dynamic organisation of detecting and repairing DNA damage. Reviews in this issue provide an update on the exciting research progress that is happening now in this field and also initiate discussion about future challenges and directions that we are heading to.

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Item Type:	Article
Authors/Creators:	Wu, Q https://orcid.org/0000-0002-6948-7043
Copyright, Publisher and Additional Information:	© 2020 The Author. This is an author produced version of an article published in Essays in Biochemistry. Uploaded in accordance with the publisher's self-archiving policy.
Keywords:	cancer, DNA damage response, DNA Repair
Dates:	Published: 26 October 2020 Published (online): 23 October 2020 Accepted: 8 October 2020
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds)
Depositing User:	Symplectic Publications
Date Deposited:	07 Dec 2020 12:58
Last Modified:	23 Oct 2021 00:38
Status:	Published
Publisher:	Portland Press
Identification Number:	10.1042/ebc20200109
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:168719

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Guardians of the genome: DNA damage and repair

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