Chau, CC orcid.org/0000-0002-3134-6798, Hewitt, EW orcid.org/0000-0002-6238-6303 and Actis, P orcid.org/0000-0002-7146-1854 (2021) The role of macromolecular crowding in single-entity electrochemistry: Friend or foe? Current Opinion in Electrochemistry, 25. 100654. ISSN 2451-9103
Abstract
The recent development of nanoscale probes has enabled the study of single molecules and single cells with unprecedented resolution and the expansion of the field of single-entity electrochemistry. There is a growing evidence suggesting that highly crowded intracellular environment facilitate nanoelectrochemical measurements in cells by improving the signal-to-noise ratio. In this opinion piece, we discuss the concept of macromolecular crowding and its implications in single-entity electrochemistry.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2020 Elsevier B.V. All rights reserved. This is an author produced version of an article published in Current Opinion in Electrochemistry. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Macromolecular crowding; Cell biology; Electrochemistry; Single-entity; Nanopipette; Single molecule; Nanopore |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Electronic & Electrical Engineering (Leeds) > Pollard Institute (Leeds) The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 16 Nov 2020 16:16 |
Last Modified: | 16 Nov 2021 01:38 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.coelec.2020.100654 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:168007 |
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