Spedalieri, Gaetana, Piersimoni, Lolita, Laurino, Omar et al. (2 more authors) (2020) Detecting and tracking bacteria with quantum light. Physical Review Research. 043260. ISSN 2643-1564
Abstract
The field of quantum sensing aims at improving the detection and estimation of classical parameters that are encoded in physical systems by resorting to quantum sources of light and quantum detection strategies. The same approach can be used to improve the current classical measurements that are performed on biological systems. Here we consider the scenario of two bacteria (E. coli and Salmonella) growing in a Luria Bertani broth and monitored by classical spectrophotometers. Their concentration can be related to the optical transmissivity via the Beer-Lambert-Bouguer's law and their growth curves can be described by means of Gompertz functions. Starting from experimental data points, we extrapolate the growth curves of the two bacteria and we study the theoretical performance that would be achieved with a quantum setup. In particular, we discuss how the bacterial growth can in principle be tracked by irradiating the samples with orders of magnitude fewer photons, identifying the clear superiority of quantum light in the early stages of growth. We then show the superiority and the limits of quantum resources in two basic tasks: (i) the early detection of bacterial growth and (ii) the early discrimination between two bacteria species.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | Comments are welcome. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details. |
Keywords: | quant-ph,physics.bio-ph,physics.med-ph,physics.optics |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Computer Science (York) |
Depositing User: | Pure (York) |
Date Deposited: | 28 Oct 2020 14:30 |
Last Modified: | 16 Oct 2024 17:03 |
Published Version: | https://doi.org/10.1103/PhysRevResearch.2.043260 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1103/PhysRevResearch.2.043260 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:167296 |