Maneffa, Andrew J., Whitwood, Adrian C., Whitehouse, A. Steve et al. (3 more authors) (2020) Unforeseen crystal forms of the natural osmolyte floridoside. Communications Chemistry. 128. ISSN 2399-3669
Abstract
Floridoside (2-α-O-D-galactopyranosyl glycerol) is a glycerol glycoside that is biosynthesised by most species of red algae and has been implicated as an intracellular regulator of various homeostatic functions. Here, we report the identification of two unforeseen crystal forms of the ubiquitous natural osmolyte floridoside including a seemingly unheralded second anhydrous conformational polymorph and the unambiguous description of an elusive monohydrated variant. By employing a variety of thermal and spectroscopic techniques, we begin to explore both their macro and molecular physicochemical properties, which are notably different to that of the previously reported polymorph. This work advances the characterisation of this important natural biomolecule which could aid in facilitating optimised utilisation across a variety of anthropocentric applications and improve comprehension of its role in-vivo as a preeminent compatible solute.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2020. |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 21 Sep 2020 11:40 |
Last Modified: | 06 Jan 2025 00:15 |
Published Version: | https://doi.org/10.1038/s42004-020-00376-z |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1038/s42004-020-00376-z |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:165753 |