Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels

Shi, J orcid.org/0000-0003-2179-8579, Hyman, AJ orcid.org/0000-0003-0874-6678, De Vecchis, D orcid.org/0000-0002-7732-5095 et al. (8 more authors) (2020) Sphingomyelinase Disables Inactivation in Endogenous PIEZO1 Channels. Cell Reports, 33 (1). 108225. ISSN 2211-1247

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Item Type: Article
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Copyright, Publisher and Additional Information:

© 2020 The Authors. This is an open access article under the terms of the Creative Commons Attribution License (CC-BY) (https://creativecommons.org/licenses/by/4.0/)

Keywords: PIEZO1; inactivation; endothelium; sphingomyelinase; SMPD3; ceramide; sphingomyelin; mechanically activated channel; molecular dynamics; simualtions
Dates:
  • Accepted: 11 September 2020
  • Published (online): 6 October 2020
  • Published: 6 October 2020
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
Funding Information:
Funder
Grant number
British Heart Foundation
FS/17/2/32559
British Heart Foundation
RG/17/11/33042
MRC (Medical Research Council)
MR/R01745X/1
Wellcome Trust
110044/Z/15/Z
Depositing User: Symplectic Publications
Date Deposited: 16 Sep 2020 15:08
Last Modified: 08 Jan 2025 12:24
Status: Published
Publisher: Cell Press
Identification Number: 10.1016/j.celrep.2020.108225
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