Slater, TA orcid.org/0000-0001-9213-5559, Cupido, B, Parry, H et al. (10 more authors) (2020) Implantable cardioverter‐defibrillator therapy to reduce sudden cardiac death in adults with congenital heart disease: A registry study. Journal of Cardiovascular Electrophysiology, 31 (8). pp. 2086-2092. ISSN 1045-3873
Abstract
Introduction:
The adult congenital heart disease (ACHD) population is rapidly expanding. However, a significant proportion of these patients suffer sudden cardiac death. Recommending implantable cardioverter‐defibrillator (ICD) insertion requires balancing the need for appropriate therapy in malignant arrhythmia against the consequences of inappropriate therapy and procedural complications. Here we present long‐term follow‐up data for ICD insertion in patients with ACHD from a large Level 1 congenital cardiac center.
Methods and Results:
All patients with ACHD undergoing ICD insertion over an 18‐year period were identified. Data were extracted for baseline characteristics including demographics, initial diagnosis, ventricular function, relevant medication, and indication for ICD insertion. Details regarding device insertion were gathered along with follow‐up data including appropriate and inappropriate therapy and complications. A total of 136 ICDs were implanted during this period: 79 for primary and 57 for secondary prevention. The most common congenital cardiac conditions in both groups were tetralogy of Fallot and transposition of the great arteries. Twenty‐two individuals in the primary prevention group received appropriate antitachycardia pacing (ATP), 14 underwent appropriate cardioversion, 17 received inappropriate ATP, and 15 received inappropriate cardioversion. In the secondary prevention group, 18 individuals received appropriate ATP, 8 underwent appropriate cardioversion, 8 received inappropriate ATP, and 7 were inappropriately cardioverted. Our data demonstrate low complication rates, particularly with leads without advisories.
Conclusion:
ICD insertion in the ACHD population involves a careful balance of the risks and benefits. Our data show a significant proportion of patients receiving appropriate therapy indicating that ICDs were inserted appropriately.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2020 Wiley Periodicals LLC. This is the peer reviewed version of the following article: Slater, TA, Cupido, B, Parry, H, et al. Implantable cardioverter‐defibrillator therapy to reduce sudden cardiac death in adults with congenital heart disease: A registry study. J Cardiovasc Electrophysiol. 2020; 31: 2086‐ 2092, which has been published in final form at https://doi.org/10.1111/jce.14633. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
Keywords: | adult congenital heart disease; implantable cardioverter‐defibrillator; sudden cardiac death |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Clinical & Population Science Dept (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 20 Aug 2020 15:28 |
Last Modified: | 24 Jun 2021 00:40 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1111/jce.14633 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:164685 |