Waite, Jessica L, Swain, Sunita, Lynch, Penelope A et al. (4 more authors) (2017) Increasing the potential for malaria elimination by targeting zoophilic vectors. Scientific Reports. p. 40551. ISSN 2045-2322
Abstract
Countries in the Asia Pacific region aim to eliminate malaria by 2030. A cornerstone of malaria elimination is the effective management of Anopheles mosquito vectors. Current control tools such as insecticide treated nets or indoor residual sprays target mosquitoes in human dwellings. We find in a high transmission region in India, malaria vector populations show a high propensity to feed on livestock (cattle) and rest in outdoor structures such as cattle shelters. We also find evidence for a shift in vector species complex towards increased zoophilic behavior in recent years. Using a malaria transmission model we demonstrate that in such regions dominated by zoophilic vectors, existing vector control tactics will be insufficient to achieve elimination, even if maximized. However, by increasing mortality in the zoophilic cycle, the elimination threshold can be reached. Current national vector control policy in India restricts use of residual insecticide sprays to domestic dwellings. Our study suggests substantial benefits of extending the approach to treatment of cattle sheds, or deploying other tactics that target zoophilic behavior. Optimizing use of existing tools will be essential to achieving the ambitious 2030 elimination target.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2017 |
Keywords: | Animals,Anopheles/physiology,Cattle,Disease Eradication,Feeding Behavior,Host-Pathogen Interactions,Humans,India,Malaria/parasitology,Models, Biological,Mosquito Vectors/physiology,Sporozoites/physiology |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Biology (York) |
Depositing User: | Pure (York) |
Date Deposited: | 15 Jul 2020 15:50 |
Last Modified: | 21 Jan 2025 17:48 |
Published Version: | https://doi.org/10.1038/srep40551 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1038/srep40551 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:163308 |