PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer

Brunner, A., Suryo Rahmanto, A., Johansson, H. et al. (10 more authors) (2020) PTEN and DNA-PK determine sensitivity and recovery in response to WEE1 inhibition in human breast cancer. eLife, 9. e57894.

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Brunner, A.
  • Suryo Rahmanto, A.
  • Johansson, H.
  • Franco, M.
  • Viiliäinen, J.
  • Gazi, M.
  • Frings, O.
  • Fredlund, E.
  • Spruck, C.
  • Lehtiö, J.
  • Rantala, J.K. ORCID logo https://orcid.org/0000-0002-4999-5585
  • Larsson, L-G.
  • Sangfelt, O.
Copyright, Publisher and Additional Information:

© 2020 The Authors. This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited. https://creativecommons.org/licenses/by/4.0/

Keywords: AZD1775; DNA-PK; PTEN; WEE1; basal-like breast cancer; cancer biology; cyclin E; mouse
Dates:
  • Accepted: 22 June 2020
  • Published: 6 July 2020
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Oncology (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 13 Jul 2020 13:23
Last Modified: 13 Jul 2020 13:30
Status: Published
Publisher: eLife Sciences Publications, Ltd
Refereed: Yes
Identification Number: 10.7554/elife.57894
Open Archives Initiative ID (OAI ID):

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