Straw, S orcid.org/0000-0002-2942-4574, Waduud, MA orcid.org/0000-0001-5567-9952, Drozd, M orcid.org/0000-0003-0255-4624 et al. (6 more authors) (2020) The role of cardiopulmonary exercise testing and echocardiography prior to elective endovascular aneurysm repair. The Annals of The Royal College of Surgeons of England, 102 (5). pp. 383-390. ISSN 0035-8843
Abstract
Introduction:
Cardiopulmonary exercise testing (CPET) and transthoracic echocardiography (TTE) are common preparative investigations prior to elective endovascular aneurysm repair (EVAR). Whether these investigations can predict survival following EVAR and contribute to shared decision making is unknown.
Methods:
Patients who underwent EVAR at a tertiary centre between June 2007 and December 2014 were identified from the National Vascular Registry. Variables obtained from preoperative investigations were assessed for their association with survival at three years. Regression analysis was used to determine variables that independently predicted survival at three years.
Results:
A total of 199 patients underwent EVAR during the study period. Of these, 120 had preoperative CPET and 123 had TTE. Lower forced expiratory ventilation (FEV1), ratio of FEV1 to forced vital capacity, work at peak oxygen consumption and higher ventilatory equivalent for carbon dioxide were associated with increased mortality. Variables obtained from TTE were not associated with survival at three years although there was a low incidence of left ventricular systolic dysfunction and significant valvular disease in this cohort.
Conclusions:
CPET might be a useful adjunct to assist in shared decision making in patients undergoing elective EVAR and may influence anaesthetic technique. TTE does not appear to be able to discriminate between high and low risk individuals. However, a low rate of significant ventricular dysfunction and valvular disease in patients undergoing elective EVAR may account for these findings.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | This is protected by copyright. All rights reserved. This is a published version of an article published in The Annals of The Royal College of Surgeons of England. Reproduced in accordance with the publisher's self-archiving policy. |
Keywords: | Preoperative testing; Abdominal aortic aneurysm; Endovascular; Cardiopulmonary exercise testing; Echocardiography |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Clinical & Population Science Dept (Leeds) The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 17 Jun 2020 15:31 |
Last Modified: | 01 Apr 2021 00:38 |
Status: | Published |
Publisher: | Royal College of Surgeons of England |
Identification Number: | 10.1308/rcsann.2020.0045 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:161959 |