Sherwood, James orcid.org/0000-0001-5431-2032 (2020) Suzuki-Miyaura cross coupling is not an informative reaction to demonstrate the performance of new solvents. Beilstein Journal of Organic Chemistry. pp. 1001-1005. ISSN 1860-5397
Abstract
The development and study of new solvents has become important due to a proliferation of regulations preventing or limiting the use of many conventional solvents. In this work, the suitability of the Suzuki-Miyaura reaction to demonstrate the usefulness of new solvents was evaluated, including Cyrene™, dimethyl isosorbide, ethyl lactate, 2-methyltetrahydrofuran (2-MeTHF), propylene carbonate, and γ-valerolactone (GVL). It was found that the cross coupling is often unaffected by the choice of solvent, and therefore the Suzuki-Miyaura reaction provides limited information regarding the usefulness of any particular solvent for organic synthesis.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2020, Sherwood; licensee Beilstein-Institut. |
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 12 Jun 2020 13:40 |
Last Modified: | 16 Oct 2024 16:40 |
Published Version: | https://doi.org/10.3762/bjoc.16.89 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.3762/bjoc.16.89 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:161873 |