Borysewicz-Sańczyk, H., Sawicka, B., Michalak, J. et al. (8 more authors) (2020) Case report: A 10-year-old girl with primary hypoparathyroidism and systemic lupus erythematosus. Journal of Pediatric Endocrinology and Metabolism, 33 (9). pp. 1231-1235. ISSN 0334-018X
Abstract
Hypoparathyroidism is a rare disease in children that occurs as a result of autoimmune destruction of the parathyroid glands, a defect in parathyroid gland development or secondary to physical parathyroid gland disturbance. Typical symptoms of hypoparathyroidism present as hypocalcaemia and hyperphosphatemia due to decreased parathyroid hormone secretion and may lead to nerve and muscles disturbances resulting in clinical manifestation of tetany, arrhythmias and epilepsy. Currently, there is no conventional hormone replacement treatment for hypoparathyroidism and therapeutic approaches include normalising mineral levels using an oral calcium supplement and active forms of vitamin D. We present the case of a 10-year old girl with primary hypoparathyroidism who had no prior history of autoimmune disorders, but who subsequently developed systemic lupus erythematosus.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2020 Walter de Gruyter GmbH, Berlin/Boston. This is an author-produced version of a paper subsequently published in Journal of Pediatric Endocrinology and Metabolism. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | primary hypoparathyroidism; hypocalcaemia; hyperphosphatemia; parathyroid hormone; systemic lupus erythematosus; autoimmune polyglandular syndrome |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Sheffield Teaching Hospitals |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 18 May 2020 14:40 |
Last Modified: | 19 Jan 2022 11:14 |
Status: | Published |
Publisher: | De Gruyter |
Refereed: | Yes |
Identification Number: | 10.1515/jpem-2020-0015 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:160849 |