Schaefer, Charley, Laity, Peter R., Holland, Chris et al. (1 more author) (2020) Silk Protein Solution:A Natural Example of Sticky Reptation. MACROMOLECULES. pp. 2669-2676. ISSN 0024-9297
Abstract
Silk is one of the most intriguing examples of biomolecular self-assembly, yet little is understood of molecular mechanisms behind the flow behavior generating these complex high-performance fibers. This work applies the polymer physics of entangled solution rheology to present a first microphysical understanding of silk in the linear viscoelastic regime. We show that silk solutions can be approximated as reptating polymers with "sticky" calcium bridges whose strength can be controlled through the potassium concentration. This approach provides a new window into critical microstructural parameters, in particular identifying the mechanism by which potassium and calcium ions are recruited as a powerful viscosity control in silk. Our model constitutes a viable starting point to understand not only the "flow-induced self-assembly" of silk fibers but also a broader range of phenomena in the emergent field of material-focused synthetic biology.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2020 American Chemical Society |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Physics (York) |
Funding Information: | Funder Grant number EPSRC EP/N031431/2 |
Depositing User: | Pure (York) |
Date Deposited: | 07 May 2020 11:00 |
Last Modified: | 24 Oct 2024 00:09 |
Published Version: | https://doi.org/10.1021/acs.macromol.9b02630 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1021/acs.macromol.9b02630 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:160451 |