Young, CA orcid.org/0000-0001-5709-4413, Gracie, DJ orcid.org/0000-0001-9616-981X, Subramanian, V orcid.org/0000-0003-3603-0861 et al. (1 more author) (2017) Amoebic colitis. Diagnostic Histopathology, 23 (12). pp. 563-565. ISSN 1756-2317
Abstract
Amoebic colitis is caused by the parasite Entamoeba histolytica (E. histolytica). The condition is prevalent in countries with poor sanitation but is increasing within developed countries secondary to global travel and immigration. We report a case of amoebic colitis diagnosed in a patient with a clinical diagnosis of Crohn's disease and with no travel history. Colonic biopsies showed focal active colitis with ulcer slough; deeper levels looking for granulomas fortuitously revealed the amoebae. The diagnosis was confirmed by positive serology and symptomatic improvement after a course of eradication treatment. Pathologists should look for amoebae in biopsies for inflammatory bowel disease (IBD), as endoscopic and histological appearances of IBD and amoebic colitis can be similar but importantly immunosuppressive therapy is contraindicated in amoebic colitis.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 16 Apr 2020 12:28 |
Last Modified: | 17 Apr 2020 08:31 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.mpdhp.2017.11.008 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:159531 |