Elserafy, M., Abugable, A.A. orcid.org/0000-0003-1275-3328, Atteya, R. et al. (1 more author) (2018) Rad5, HLTF, and SHPRH: A fresh view of an old story. Trends in Genetics, 34 (8). pp. 574-577. ISSN 0168-9525
Abstract
Not only have helicase-like transcription factor (HLTF) and SNF2 histone-linker PHD-finger RING-finger helicase (SHPRH) proved to be important players in post-replication repair like their yeast counterpart, Rad5, but they are also involved in multiple biological functions and are associated with several human disorders. We provide here an updated view of their functions, associated diseases, and potential therapeutic approaches.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018 The Authors, published by Elsevier. Article available under the terms of the CC-BY licence (https://creativecommons.org/licenses/by/4.0/). |
Keywords: | RAD5; HLTF; SHPRH; cancer; HIV-1; bowel disease |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield) > Department of Molecular Biology and Biotechnology (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 22 Apr 2020 16:03 |
Last Modified: | 23 Apr 2020 09:31 |
Status: | Published |
Publisher: | Elsevier BV |
Refereed: | Yes |
Identification Number: | 10.1016/j.tig.2018.04.006 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:159493 |
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