Hoogkamer, A.B., Brooks, A.J., Rowse, G. orcid.org/0000-0003-3292-4008 et al. (1 more author) (2021) Predicting the development of psychological morbidity in inflammatory bowel disease : a systematic review. Frontline Gastroenterology, 12 (2). pp. 137-144. ISSN 2041-4137
Abstract
Background: Psychological morbidity in inflammatory bowel disease is common with significant impact on quality of life and health outcomes, but factors which predict the development of psychological morbidity are unclear.
Aim: To undertake a systematic literature review of the predictors of psychological morbidity in patients with inflammatory bowel disease.
Methods: Electronic searches for English-language articles were performed with keywords relating to psychological morbidity according to the Diagnostic and Statistical Manual of Mental Disorders IV and subsequent criteria, and inflammatory bowel disease; in MEDLINE, PsychInfo, Web of Science and EMBASE for studies published from January 1997 to 25 January 2019.
Results: Of 660 studies identified, seven met the inclusion criteria. All measured depression, with three also measuring anxiety. Follow-up duration was variable (median of 18 months range 6–96 months). Risk factors identified for development of psychological morbidity included physical factors: aggressive disease (HR 5.77, 95% CI 1.89 to 17.7) and greater comorbidity burden (OR 4.31, 95% CI 2.83 to 6.57) and psychological risk factors: degree of gratitude (r=−0.43, p<0.01) and parenting stress (R-change=0.03, F(1,58)=35.6, p<0.05). Age-specific risk was identified with young people (13–17 years) at increased risk.
Conclusions: Identifiable risks for the development of psychological morbidity in inflammatory bowel disease include physical and psychological factors. Further research is required from large prospective studies to enable early interventions in those at risk and reduce the impact of psychological morbidity.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2020 The Author(s). This is an author-produced version of a paper subsequently published in Frontline Gastroenterology. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | inflammatory bowel disease; psychological morbidity; prediction |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Psychology (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 02 Apr 2020 08:00 |
Last Modified: | 26 Nov 2021 16:45 |
Status: | Published |
Publisher: | BMJ Publishing Group |
Refereed: | Yes |
Identification Number: | 10.1136/flgastro-2019-101353 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:159009 |
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