Cardiac resynchronization therapy following Carillon® annuloplasty device for symptomatic heart failure and functional mitral regurgitation: a case report

Abstract

Background

Symptomatic patients with significant left ventricular systolic dysfunction (LVSD) require a tailored treatment approach. Both functional mitral regurgitation (FMR) and left bundle branch block (LBBB) can develop, contributing to clinical deterioration, and worse prognosis despite optimal medical therapy (OMT).

Case summary

We report the case of a symptomatic 60-year-old man on OMT with LVSD and significant FMR. His symptoms and FMR initially improved following transvenous mitral annuloplasty using the Carillon® Mitral Contour System® annuloplasty device. However, he subsequently developed LBBB with associated reduction in exercise capacity, for which he underwent cardiac resynchronization therapy, and ensuing symptom improvement and stabilization.

Discussion

Our case describes how targeted device interventions can be combined synergistically to optimize patient symptoms.

Metadata

Item Type:	Article
Authors/Creators:	Jamil, HA Goldberg, SL Witte, KK https://orcid.org/0000-0002-7146-7105
Copyright, Publisher and Additional Information:	©The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
Keywords:	Cardiac resynchronization therapy, Heart failure, Mitral annuloplasty, Carillon, Functional mitral regurgitation, Case report
Dates:	Accepted: 21 November 2019 Published (online): 10 December 2019 Published: December 2019
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Clinical & Population Science Dept (Leeds)
Depositing User:	Symplectic Publications
Date Deposited:	20 Feb 2020 12:43
Last Modified:	28 Feb 2020 09:52
Status:	Published
Publisher:	Oxford University Press (OUP)
Identification Number:	10.1093/ehjcr/ytz224
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:157470

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Cardiac resynchronization therapy following Carillon® annuloplasty device for symptomatic heart failure and functional mitral regurgitation: a case report

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