Vallejo-Giraldo, C, Pampaloni, NP, Pallipurath, AR orcid.org/0000-0002-9778-5160 et al. (14 more authors) (2018) Preparation of Cytocompatible ITO Neuroelectrodes with Enhanced Electrochemical Characteristics Using a Facile Anodic Oxidation Process. Advanced Functional Materials, 28 (12). 1605035. ISSN 1616-301X
Abstract
Physicochemical modification of implantable electrode systems is recognized as a viable strategy to enhance tissue/electrode integration and electrode performance in situ. In this work, a bench‐top electrochemical process to formulate anodized indium tin oxide (ITO) films with altered roughness, conducting profiles, and thickness is explored. In addition, the influence of these anodized films on neural cell adhesion, proliferation, and function indicates that anodized ITO film cytocompatibility can be altered by varying the anodization current density. Furthermore, ITO‐anodized films formed with a current density of 0.4 mA cm−2 show important primary neural cell survival, modulation of glial scar formation, and promotion of neural network activity.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Keywords: | cytocompatibility; electrodes; functionalization; indium tin oxide; neural interfaces |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemical & Process Engineering (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 18 Feb 2020 14:41 |
Last Modified: | 18 Feb 2020 14:41 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1002/adfm.201605035 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:157230 |