Leighton, RK, de Dios Robinson, J and Giannoudis, PV orcid.org/0000-0002-5205-7696 (2019) Nonunions of Bisphosphonate Fractures of the Femur Presentation, Etiopathogenesis, Diagnosis, and Operative Treatment. Journal of Orthopaedic Trauma, 33 (12). S14-S20. ISSN 0890-5339
Abstract
Patients presenting with femoral fractures and long term use of bisphosphonate treatment are at risk of developing a delayed union and/or nonunion as a result of the atypical metabolic activity prevailing at the fracture edges of the affected extremity. The treatment of these nonunions poses a serious challenge to orthopaedic surgeons worldwide and necessitates specialized techniques and materials to design a construct that will last a long period (greater than 6 months), while still allowing weight-bearing in this elderly population. Treatment options, timing of intervention, selection of implant, and the option of bone grafting are discussed to assist the clinician to make the right decisions in these complex clinical cases.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Keywords: | atypical fracture, femur, nonunion, bone grafting, bisphosphonate treatment |
Dates: |
|
Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Orthopaedics (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 13 Feb 2020 15:18 |
Last Modified: | 13 Feb 2020 15:18 |
Status: | Published |
Publisher: | Lippincott, Williams & Wilkins |
Identification Number: | 10.1097/bot.0000000000001642 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:156910 |