Conditional genome engineering reveals canonical and divergent roles for the Hus1 component of the 9-1-1 complex in the maintenance of the plastic genome of Leishmania.

Damasceno, Jeziel D, Obonaga, Ricardo, Silva, Gabriel L A et al. (6 more authors) (2018) Conditional genome engineering reveals canonical and divergent roles for the Hus1 component of the 9-1-1 complex in the maintenance of the plastic genome of Leishmania. Nucleic Acids Research. pp. 11835-11846. ISSN 0305-1048

Abstract

Metadata

Item Type: Article
Authors/Creators:
  • Damasceno, Jeziel D
  • Obonaga, Ricardo
  • Silva, Gabriel L A
  • Reis-Cunha, Joao L.
  • Duncan, Samuel M
  • Bartholomeu, Daniella C.
  • Mottram, Jeremy Charles ORCID logo https://orcid.org/0000-0001-5574-3766
  • McCulloch, Richard
  • Tosi, Luiz R O
Copyright, Publisher and Additional Information:

© The Author(s) 2018.

Keywords: Cell Cycle Proteins/deficiency,Computational Biology/methods,Culture Media/chemistry,DNA Repair Enzymes/genetics,DNA, Single-Stranded/genetics,Endonucleases/genetics,G2 Phase Cell Cycle Checkpoints/genetics,Gene Deletion,Gene Expression Regulation,Genetic Engineering,Genetic Variation,Genome, Protozoan,Genomic Instability,Histones/genetics,Leishmania major/genetics,Whole Genome Sequencing
Dates:
  • Published: 14 December 2018
  • Published (online): 31 October 2018
  • Accepted: 10 October 2018
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Biology (York)
Depositing User: Pure (York)
Date Deposited: 04 Feb 2020 11:50
Last Modified: 16 Oct 2024 15:13
Published Version: https://doi.org/10.1093/nar/gky1017
Status: Published
Refereed: Yes
Identification Number: 10.1093/nar/gky1017
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Open Archives Initiative ID (OAI ID):

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