Tesfaye, WH, Wimmer, BC, Peterson, GM et al. (4 more authors) (2019) Effect of pharmacist‐led medication review on medication appropriateness in older adults with chronic kidney disease. Journal of Pharmacy Practice and Research, 49 (5). pp. 471-476. ISSN 2055-2335
Abstract
This study evaluated the effect of pharmacist‐led review on medication appropriateness in 204 older patients with chronic kidney disease (CKD) admitted to an Australian hospital. Medication appropriateness was evaluated using the Medication Appropriateness Index (MAI) prior to medication review, after review (assuming all recommendations were accepted by physicians) and after outcome (acceptance/non‐acceptance) of recommendations. Overall, 95 patients (46%) received a medication review by pharmacists. The median (interquartile range) MAI score decreased significantly from a baseline of 7 (3–12) to 5 (2–10) after medication review (p < 0.001) and to 6 (2–10) after the outcome of recommendations (p < 0.01). The MAI score also decreased in patients with no medication review by a pharmacist from 6 (3–11) at admission to 5 (2–9) at discharge (p < 0.001). MAI scores declined markedly in people with all pharmacist‐conducted medication review recommendations accepted (from 7 to 3; p < 0.05). Reassuringly, hospitalisation alone improved medication appropriateness. However, pharmacist‐led medication review can further optimise medication appropriateness in older CKD patients, particularly when the recommendations are implemented.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2019 The Society of Hospital Pharmacists of Australia. This is the peer reviewed version of the following article: Tesfaye, W. H., Wimmer, B. C., Peterson, G. M., Castelino, R. L., Jose, M. , McKercher, C. and Zaidi, S. T. (2019), Effect of pharmacist‐led medication review on medication appropriateness in older adults with chronic kidney disease. J Pharm Pract Res, 49: 471-476. doi:10.1002/jppr.1539, which has been published in final form at https://doi.org/10.1002/jppr.1539. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | chronic kidney disease; Medication Appropriateness Index; potentially inappropriate medications |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Healthcare (Leeds) > Pharmacy (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 28 Nov 2019 14:43 |
Last Modified: | 11 Sep 2020 00:38 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1002/jppr.1539 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:153950 |