Cianciulli, A., Coulthard, L., Hawksworth, O. et al. (5 more authors) (2019) Complement peptide receptors (version 2019.4) in the IUPHAR/BPS guide to pharmacology database. IUPHAR/BPS Guide to Pharmacology CITE, 2019 (4). ISSN 2633-1020
Abstract
Complement peptide receptors (nomenclature as agreed by the NC-IUPHAR subcommittee on Complement peptide receptors [98]) are activated by the endogenous ~75 amino-acid anaphylatoxin polypeptides C3a and C5a, generated upon stimulation of the complement cascade. C3a and C5a exert their functions through binding to their receptors (C3aR and C5aR), causing cell activation and triggering cellular degranulation that contributes to the local inflammation.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2019 The Author(s). |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 04 Dec 2019 10:44 |
Last Modified: | 04 Dec 2019 10:44 |
Status: | Published |
Publisher: | Edinburgh University Library |
Refereed: | Yes |
Identification Number: | 10.2218/gtopdb/f5/2019.4 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:153755 |