Klauck, Felix J.R., Yoon, Hyung, James, Michael J. orcid.org/0000-0003-2591-0046 et al. (2 more authors) (2019) Visible-Light-Mediated Deaminative Three-Component Dicarbofunctionalization of Styrenes with Benzylic Radicals. ACS Catalysis. pp. 236-241. ISSN 2155-5435
Abstract
The visible-light-mediated three-component dicarbofunctionalization of styrenes using simple benzylic radicals is described. Notably, this work describes a rare example of undirected dicarbofunctionalization using unsubstituted benzyl radicals. Key to the success of this strategy was the rational design and use of benzylic pyridinium salts as radical precursors. Using this approach, abundant styrenes, electron-rich heterocycles, and benzylic amines were combined to rapidly afford a number of densely functionalized 1,1-diarylalkanes. A dipeptide-derived pyridinium salt was applied in this transformation, which resembles a visible-light-mediated deaminative generation of radicals from peptides.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018 American Chemical Society. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details. |
Keywords: | deamination,dicarbofunctionalization,photoredox catalysis,redox-active,visible-light |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 07 Oct 2019 15:20 |
Last Modified: | 17 Dec 2024 00:14 |
Published Version: | https://doi.org/10.1021/acscatal.8b04191 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1021/acscatal.8b04191 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:151867 |