Toward a Core Domain Set for Glucocorticoid Impact in Inflammatory Rheumatic Diseases: The OMERACT 2018 Glucocorticoid Impact Working Group

Objective: To understand the effects of glucocorticoids (GC), which are of importance to patients.

Methods: The results of 2 literature reviews, a patient survey, and a qualitative study were presented.

Results: No validated instrument exists to evaluate GC effect on patients. Survey data revealed skin thinning/bruising, sleep disturbance, and weight gain as the most frequent adverse effects. The qualitative research yielded rich data covering rapid benefits and physical and emotional consequences of GC.

Conclusion: It was agreed that a patient-reported outcome to measure GC effect was required and a research agenda was developed for this goal.