Wingender, Brian, Tong, Emma, Emery, John et al. (2 more authors) (2019) Time-Resolved in situ Raman Spectroscopic Observations of a Biomineralization Model System. Microscopy and Microanalysis. pp. 826-827. ISSN 1431-9276
Abstract
The mechanisms underlying the formation of nanocrystalline apatite in vertebrate hard tissues (i.e. bones and teeth) remain nebulous. The long-held view of biomineralization via “classical crystallization theory”, or ion-by-ion addition from solution, is challenged by “non-classical” theories in which the pathway proceeds through transient precursor phases [1]. The presence of an amorphous calcium phosphate (ACP) mineral precursor has been observed during the formation of zebrafish fin bones and dental enamel [2, 3]. However, the sample preparation necessary for electron microscopy and ethical considerations inherent to vertebrate samples preclude in situ observations of apatite mineralization.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © Microscopy Society of America 2019. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details. |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Physics (York) |
Depositing User: | Pure (York) |
Date Deposited: | 17 Sep 2019 09:20 |
Last Modified: | 16 Oct 2024 15:58 |
Published Version: | https://doi.org/10.1017/S1431927619004860 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1017/S1431927619004860 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:150841 |