Griffin, J. orcid.org/0000-0003-3969-7637, Allsobrook, O., Khurram, S.A. orcid.org/0000-0002-0378-9380 et al. (3 more authors) (2018) EBV-associated ulceration in an immunocompromised patient. Diagnostic Histopathology, 24 (7). pp. 267-271. ISSN 1756-2317
Abstract
Epstein Barr virus-positive mucocutaneous ulceration (EBVMCU) is an uncommon entity first described in 2010. This lymphoproliferative disorder was first described in immunocompromised patients presenting with well-defined ulceration involving the oral cavity, skin and gastrointestinal tract. The first case series suggested that EBVMCU is generally self-limiting and likely to resolve without treatment. However, since then, additional cases reported have described a more heterogeneous course. Many people are infected with Epstein Barr virus (EBV) at a young age and this usually has a self-limiting course. However, immunosuppression due to any cause, including age-related immunosenescene may facilitate a wide spectrum of EBV-related lymphoid hyperplasia and lymphoma. We describe a case of oral presentation of EBVMU in a patient on long term immunosuppressants.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018 Elsevier. |
Keywords: | EBV; lymphoproliferative disorders; immunocompromise; oral ulceration |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Clinical Dentistry (Sheffield) The University of Sheffield > Faculty of Science (Sheffield) > School of Biosciences (Sheffield) > Department of Molecular Biology and Biotechnology (Sheffield) The University of Sheffield > Sheffield Teaching Hospitals |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 04 Sep 2019 13:18 |
Last Modified: | 04 Sep 2019 13:18 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.mpdhp.2018.05.007 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:150423 |