Ha, Jun Yong, Chou, Hui-Ting, Ungar, Daniel orcid.org/0000-0002-9852-6160 et al. (3 more authors) (2016) Molecular architecture of the complete COG tethering complex. Nature Structural & Molecular Biology. pp. 758-760. ISSN 1545-9993
Abstract
The conserved oligomeric Golgi (COG) complex orchestrates vesicular trafficking to and within the Golgi apparatus. Here, we use negative-stain electron microscopy to elucidate the architecture of the hetero-octameric COG complex from Saccharomyces cerevisiae. Intact COG has an intricate shape, with four (or possibly five) flexible legs, that differs strikingly from that of the exocyst complex and appears to be well suited for vesicle capture and fusion.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details. Embargo period: 6 months [paper and supplementary file] |
Keywords: | Adaptor Proteins, Vesicular Transport/ultrastructure,Golgi Apparatus/ultrastructure,Microscopy, Electron,Multiprotein Complexes/ultrastructure,Protein Structure, Quaternary,Saccharomyces cerevisiae Proteins/ultrastructure,Saccharomyces cerevisiae/ultrastructure |
Dates: |
|
Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Biology (York) |
Funding Information: | Funder Grant number EUROPEAN COMMISSION MIRG-CT-2007-201098 |
Depositing User: | Pure (York) |
Date Deposited: | 10 Jul 2019 13:10 |
Last Modified: | 16 Oct 2024 13:06 |
Published Version: | https://doi.org/10.1038/nsmb.3263 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.1038/nsmb.3263 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:148432 |
Download
Filename: Ha_et_al._NSMB_accepted_version_2016.pdf
Description: Ha et al. NSMB accepted version 2016