Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG):Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides

• Waszkowycz, Bohdan
• Smith, Kate M.
• McGonagle, Alison E.
• Jordan, Allan M.
• Acton, Ben
• Fairweather, Emma E.
• Griffiths, Louise A.
• Hamilton, Niall M.
• Hamilton, Nicola S.
• Hitchin, James R.
• Hutton, Colin P.
• James, Dominic I.
• Jones, Clifford D.
• Jones, Stuart
• Mould, Daniel P.
• Small, Helen F.
• Stowell, Alexandra I. J.
• Tucker, Julie Ann https://orcid.org/0000-0002-6119-676X
• Waddell, Ian D.
• Ogilvie, Donald J.

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• Published: 13 December 2018
• Published (online): 7 November 2018
• Accepted: 7 November 2018