Rodríguez‐Sánchez, J., Myszka, B., Boccaccini, A.R. et al. (1 more author) (2019) Setting behavior and bioactivity assessment of calcium carbonate cements. Journal of the American Ceramic Society, 102 (11). pp. 6980-6990. ISSN 0002-7820
Abstract
Calcium carbonate cements have emerged in the last few years as an attractive candidate for biomedical applications. They can be easily prepared by mixing water with two metastable calcium carbonate phases––amorphous calcium carbonate (ACC) and vaterite––which (re)crystallize into calcite during setting reaction. The transformation kinetics (and therefore the final surface cement composition) strongly depends on the initial mixture design and is controlled by the dissolution of ACC, whereas calcite nucleation typically controls their recrystallization in fluid batch experiments. Novel compositions are presented in this paper by incorporating organic molecules as a proxy to test their capability to carry on other biomolecules like proteins or antibiotics. The hardened samples are microporous and show excellent bioactivity rates, although their mechanical properties still remain poor. However, this would not be a handicap for in‐vivo applications such as bone filling, especially in low mechanical stress locations.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2019 The Authors. This is an open access article under the terms of the Creative Commons Attribution‐Non-Commercial‐No Derivatives License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. |
Keywords: | (re)crystallization kinetics; apatite‐like precipitation; bioactivity; CaCO3 cements; compressive strength |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Engineering (Sheffield) > Department of Materials Science and Engineering (Sheffield) |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 05 Jul 2019 10:29 |
Last Modified: | 07 Dec 2021 10:21 |
Status: | Published |
Publisher: | Wiley |
Refereed: | Yes |
Identification Number: | 10.1111/jace.16593 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:147308 |
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