BK virus: Current understanding of pathogenicity and clinical disease in transplantation

Abstract

BK polyomavirus (BKV) is an important cause of graft loss in renal transplant recipients that continues to pose a significant challenge to clinicians due to its frequently unpredictable onset, persistence, and the lack of effective antiviral agents or prevention strategies. This review covers our current understanding of epidemiology, viral transmission and disease progression, and treatment and prevention strategies that have been used to manage this disease.

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Item Type:	Article
Authors/Creators:	Chong, S Antoni, M https://orcid.org/0000-0002-3641-7559 Macdonald, A https://orcid.org/0000-0002-5978-4693 Reeves, M Harber, M Magee, CN
Copyright, Publisher and Additional Information:	© 2019 John Wiley & Sons, Ltd. This is an author produced version of a paper published in Reviews in Medical Virology. Uploaded in accordance with the publisher's self-archiving policy.
Dates:	Published: July 2019 Published (online): 8 April 2019 Accepted: 1 March 2019
Institution:	The University of Leeds
Academic Units:	The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds)
Funding Information:	Funder Grant number Kidney Research Yorkshire Not Known Kidney Research UK Not Known Kidney Research Yorkshire Not Known Kidney Research UK RP_022_20170302 Kidney Research UK ST_002_20171124
Depositing User:	Symplectic Publications
Date Deposited:	05 Jun 2019 10:34
Last Modified:	08 Apr 2020 00:38
Status:	Published
Publisher:	Wiley
Identification Number:	10.1002/rmv.2044
Open Archives Initiative ID (OAI ID):	oai:eprints.whiterose.ac.uk:146942

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BK virus: Current understanding of pathogenicity and clinical disease in transplantation

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