Douglas, GE, Raw, SA and Marsden, SP orcid.org/0000-0002-2723-8954 (2019) Iron‐Catalysed Direct Aromatic Amination with N‐Chloroamines. European Journal of Organic Chemistry, 2019 (31-32). pp. 5508-5514. ISSN 1434-193X
Abstract
An optimized procedure for the direct intra‐ and intermolecular amination of aromatic C‐H bonds with aminium radicals generated from N‐chloroamines under iron catalysis is reported. A range of substituted tetrahydroquinolines could be readily prepared, while extension to the synthesis of benzomorpholines was more limited in scope. A direct one‐pot variant was developed, allowing direct formal oxidative N‐H/C‐H coupling.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2019 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim. This is the peer reviewed version of the following article: Douglas, G. E., Raw, S. A. and Marsden, S. P. (2019), Iron‐Catalysed Direct Aromatic Amination with N‐Chloroamines. Eur. J. Org. Chem., 2019: 5508-5514, which has been published in final form at https://doi.org/10.1002/ejoc.201900614. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Amination; Arylamines; Radicals; Homogeneous catalysis; Tetrahydroquinolines |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 15 May 2019 13:25 |
Last Modified: | 13 May 2020 00:38 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1002/ejoc.201900614 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:146048 |