Turicchi, J, O'Driscoll, R orcid.org/0000-0003-3995-0073, Finlayson, G orcid.org/0000-0002-5620-2256 et al. (3 more authors) (2019) Associations between the rate, amount, and composition of weight loss as predictors of spontaneous weight regain in adults achieving clinically significant weight loss: A systematic review and meta-regression. Obesity Reviews, 20 (7). pp. 935-946. ISSN 1467-7881
Abstract
Weight regain following weight loss is common although little is known regarding the associations between amount, rate, and composition of weight loss and weight regain. Forty-three studies (52 groups; n = 2379) with longitudinal body composition measurements were identified in which weight loss (≥5%) and subsequent weight regain (≥2%) occurred. Data were synthesized for changes in weight and body composition. Meta-regression models were used to investigate associations between amount, rate, and composition of weight loss and weight regain. Individuals lost 10.9% of their body weight over 13 weeks composed of 19.6% fat-free mass, followed by a regain of 5.4% body weight over 44 weeks composed of 21.6% fat-free mass. Associations between the amount (P < 0.001) and rate (P = 0.049) of weight loss and their interaction (P = 0.042) with weight regain were observed. Fat-free mass (P = 0.017) and fat mass (P < 0.001) loss both predicted weight regain although the effect of fat-free mass was attenuated following adjustment. The amount (P < 0.001), but not the rate of weight loss (P = 0.150), was associated with fat-free mass loss. The amount and rate of weight loss were significant and interacting factors associated with weight regain. Loss of fat-free mass and fat mass explained greater variance in weight regain than weight loss alone.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2019 World Obesity Federation. This is the post-peer reviewed version of the following article: Turicchi, J, O'Driscoll, R , Finlayson, G et al. (3 more authors) (2019) Associations between the rate, amount, and composition of weight loss as predictors of spontaneous weight regain in adults achieving clinically significant weight loss: A systematic review and meta-regression. Obesity Reviews, which has been published in final form at https://doi.org/10.1111/obr.12849. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. |
Keywords: | body composition; fat mass; fat‐free mass; weight loss; weight regain |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Psychology (Leeds) |
Funding Information: | Funder Grant number EU - European Union 643309 |
Depositing User: | Symplectic Publications |
Date Deposited: | 10 May 2019 10:48 |
Last Modified: | 30 Mar 2020 00:40 |
Status: | Published |
Publisher: | Wiley |
Identification Number: | 10.1111/obr.12849 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:145834 |