Scully, SM, Brown, A, Ross, AB et al. (1 more author) (2019) Biotransformation of organic acids to their corresponding alcohols by Thermoanaerobacter pseudoethanolicus. Anaerobe, 57. pp. 28-31. ISSN 1075-9964
Abstract
Higher order alcohols, such as 1-butanol and 1-hexanol, have a large number of applications but are currently prepared from non-renewable feedstocks. Here, the ability of Thermoanaerobacter pseudoethanolicus to reduce short-chain fatty acids to their corresponding alcohols using reducing potential generated by glucose catabolism with yields between 21.0 and 61.0%. 13 C-labelled acetate, 1-propionate and 1-butyrate demonstrates that exogenously added fatty acids are indeed reduced to their corresponding alcohols. This mode of producing primary alcohols from fatty acids using a thermophilic anaerobe opens the door for the production of such alcohols from low-value materials using an inexpensive source of reducing potential.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | (c) 2019, Elsevier Ltd. All rights reserved. This is an author produced version of a paper published in Anaerobe. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Butanol; Propanol; Hexanol; Bioreduction; Thermophiles; Biocatalysis |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Engineering & Physical Sciences (Leeds) > School of Chemical & Process Engineering (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 30 Apr 2019 15:33 |
Last Modified: | 12 Mar 2020 01:38 |
Status: | Published |
Publisher: | Elsevier |
Identification Number: | 10.1016/j.anaerobe.2019.03.004 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:145430 |