Avello Fernández, Paula Andrea, Davis, Seth Jon orcid.org/0000-0001-5928-9046, Ronald, James Andrew orcid.org/0000-0002-8847-0378 et al. (1 more author) (2019) Heat the Clock:Entrainment and Compensation in Arabidopsis Circadian Rhythms. Journal of circadian rhythms. ISSN 1740-3391
Abstract
The circadian clock is a biological mechanism that permits some organisms to anticipate daily environmental variations. This clock generates biological rhythms, which can be reset by environmental cues such as cycles of light or temperature, a process known as entrainment. After entrainment, circadian rhythms typically persist with approximately 24 hours periodicity in free-running conditions i.e. in the absence of environmental cues. Experimental evidence also shows that a free-running period close to 24 hours is maintained across a range of temperatures, a process known as temperature compensation. In the plant Arabidopsis, the effect of light on the circadian system has been widely studied and successfully modelled mathematically. However, the role of temperature in periodicity, and the relationships between entrainment and compensation, are not fully understood. Here we adapt recent models to incorporate temperature dependence by applying Arrhenius equations to the parameters of the models that characterize transcription, translation, and degradation rates. We show that the resulting models can exhibit thermal entrainment and temperature compensation, but that these phenomena emerge from physiologically different sets of processes. Further simulations combining thermal and photic forcing in more realistic scenarios clearly distinguish between the processes of entrainment and compensation, and reveal temperature compensation as an emergent property which can arise as a result of multiple temperature-dependent interactions. Our results consistently point to the thermal sensitivity of degradation rates as driving compensation and entrainment across a range of conditions.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2019 The Author(s). |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Mathematics (York) The University of York > Faculty of Sciences (York) > Biology (York) The University of York > Faculty of Sciences (York) > Chemistry (York) |
Depositing User: | Pure (York) |
Date Deposited: | 23 Apr 2019 14:10 |
Last Modified: | 21 Jan 2025 17:39 |
Published Version: | https://doi.org/10.5334/jcr.179 |
Status: | Published |
Refereed: | Yes |
Identification Number: | 10.5334/jcr.179 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:145258 |