Paton, MF and Witte, KK orcid.org/0000-0002-7146-7105 (2019) Heart failure and right ventricular pacing - how to avoid the need for cardiac resynchronization therapy. Expert Review of Medical Devices, 16 (1). pp. 35-43. ISSN 1743-4440
Abstract
Introduction: Heart failure (HF) is a common finding in patients with pacemakers implanted for bradycardia, with cross-sectional and longitudinal studies contributing to the growing consensus that right ventricular pacing can cause adverse cardiac remodeling and left ventricular systolic dysfunction increasing the risk of hospitalization and death.
An unselected approach using cardiac resynchronization therapy from the time of first implant in patients with heart block has produced equivocal results. Contemporary research has therefore begun to focus on the stratification of patients’ risk of pacemaker-associated impairment to permit focused, personalized management.
Areas covered: The present review will describe the incidence and relevance of HF in the pacemaker population and discuss current management options for such patients.
Expert commentary: At present there are few contemporary data to guide the identification of patients with and at risk of pacemaker-associated cardiac remodeling and dysfunction. Emphasis must be placed on precise and personalized treatment approaches which currently remain under-investigated due to a number of challenges, for example, small sample sizes, limited clarity on programmed settings, and short follow-up periods.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2018, Taylor & Francis. This is an author produced version of a paper published in Expert Review of Medical Devices. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Bradycardia; heart failure; pacemaker; ventricular dysfunction; cardiac device |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Clinical & Population Science Dept (Leeds) |
Funding Information: | Funder Grant number NIHR National Inst Health Research NIHR-CS--012-032 NIHR National Inst Health Research ICA-CDRF-2016-02-055 |
Depositing User: | Symplectic Publications |
Date Deposited: | 06 Mar 2019 14:00 |
Last Modified: | 26 Nov 2019 01:39 |
Status: | Published |
Publisher: | Taylor & Francis |
Identification Number: | 10.1080/17434440.2019.1552133 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:143338 |