Hukins, Deborah orcid.org/0000-0003-0101-3033, Macleod, Una and Boland, Jason W (2019) Identifying potentially inappropriate prescribing in older people with dementia:a systematic review. European journal of clinical pharmacology. ISSN 1432-1041
Abstract
PURPOSE: Older people with dementia are at risk of adverse events associated with potentially inappropriate prescribing. AIM: to describe (1) how international tools designed to identify potentially inappropriate prescribing have been used in studies of older people with dementia, (2) the prevalence of potentially inappropriate prescribing in this cohort and (3) advantages/disadvantages of tools METHODS: Systematic literature review, designed and reported according to the Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P). MEDLINE, EMBASE, PsychInfo, CINAHL, the Cochrane Library, the Social Science Citation Index, OpenGrey, Base, GreyLit, Mednar and the National Database of Ageing Research were searched in April 2016 for studies describing the use of a tool or criteria to identify potentially inappropriate prescribing in older people with dementia. RESULTS: Three thousand three hundred twenty-six unique papers were identified; 26 were included in the review. Eight studies used more than one tool to identify potentially inappropriate prescribing. There were variations in how the tools were applied. The Beers criteria were the most commonly used tool. Thirteen of the 15 studies using the Beers criteria did not use the full tool. The prevalence of potentially inappropriate prescribing ranged from 14 to 74% in older people with dementia. Benzodiazepines, hypnotics and anticholinergics were the most common potentially inappropriately prescribed medications. CONCLUSIONS: Variations in tool application may at least in part explain variations in potentially inappropriate prescribing across studies. Recommendations include a more standardised tool usage and ensuring the tools are comprehensive enough to identify all potentially inappropriate medications and are kept up to date.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2019 |
Dates: |
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Institution: | The University of York |
Academic Units: | The University of York > Faculty of Sciences (York) > Health Sciences (York) The University of York > Faculty of Sciences (York) > Hull York Medical School (York) |
Depositing User: | Pure (York) |
Date Deposited: | 28 Feb 2019 15:00 |
Last Modified: | 07 Feb 2025 00:23 |
Published Version: | https://doi.org/10.1007/s00228-018-02612-x |
Status: | Published online |
Refereed: | Yes |
Identification Number: | 10.1007/s00228-018-02612-x |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:143113 |
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Description: Identifying potentially inappropriate prescribing in older people with dementia: a systematic review