Nwosu, A., Mayland, C. orcid.org/0000-0002-1440-9953, Mason, S. et al. (4 more authors) (2019) Bioelectrical impedance vector analysis (BIVA) as a method to compare body composition differences according to cancer stage and type. Clinical Nutrition ESPEN, 30. pp. 59-66. ISSN 2405-4577
Abstract
Background & Aims
Bioelectrical impedance vector analysis (BIVA) is a non-invasive method of measuring human body composition . This offers the potential to evaluate nutritional and hydration states in cancer. Analysis of BIVA data using z-score (the number of standard deviations away from the mean value of the reference group) has the potential to facilitate comparisons between different cancer types.
The aim of this study was to use the BIVA Reactance (R) / Reactance (Xc) z-score method to evaluate body composition differences in cancer, using data from previously published BIVA studies.
Methods
Previous studies using BIVA in cancer were identified from the literature. Bioimpedance measures were analysed using the BIVA RXc z-score graph. The mean vector impedance measures from the studied populations were transformed into standard deviates (with respect to the mean and standard deviation of the reference populations). Body composition was classified according to vector placement (i.e. normal athletic, cachectic, oedematous and dehydrated).
Results
Seven male and three cancer female populations were evaluated. Body composition was classified as normal for the majority (n=5), followed by cachexia (n=4) and athletic (n=1) respectively. Variation in body composition for the studied populations appeared to be related to factors, such as gender, disease type and severity.
Conclusions
The BIVA RXc z-score method has potential to evaluate body composition differences between cancer groups. This method can study body composition, according to cancer type, stage, gender and ethnicity. Limitations of the method relate to issues appropriate reference populations and variability between bioimpedance analysers. Better body composition assessment has the potential to personalise therapeutic, nutrition and hydration management. Further work is essential to facilitate in-depth evaluation in these areas, in order to achieve meaningful use of the BIVA method in clinical practice.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2019 The Authors. This is an author produced version of a paper subsequently published in Clinical nutrition ESPEN. Uploaded in accordance with the publisher's self-archiving policy. Article available under the terms of the CC-BY-NC-ND licence (https://creativecommons.org/licenses/by-nc-nd/4.0/). |
Keywords: | Bioelectrical impedance vector analysis; Bioelectrical impedance analysis; nutritional assessment; cancer; body composition; palliative care |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Sheffield Teaching Hospitals |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 19 Feb 2019 11:30 |
Last Modified: | 18 Nov 2021 10:43 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1016/j.clnesp.2019.02.006 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:142724 |