Disruption of key NADH-binding pocket residues of the Mycobacterium tuberculosis InhA affects DD-CoA binding ability

Shaw, Daniel J, Robb, Kirsty, Vetter, Beatrice V et al. (4 more authors) (2017) Disruption of key NADH-binding pocket residues of the Mycobacterium tuberculosis InhA affects DD-CoA binding ability. Scientific Reports. 4714. p. 4714. ISSN 2045-2322

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Item Type: Article
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© The Author(s) 2017

Keywords: Acyl Coenzyme A/metabolism,Bacterial Proteins/chemistry,Binding Sites,Catalytic Domain,Hydrophobic and Hydrophilic Interactions,Kinetics,Mutagenesis, Site-Directed,Mycobacterium tuberculosis/genetics,NAD/genetics,Oxidoreductases/chemistry,Protein Binding
Dates:
  • Published: 1 December 2017
  • Accepted: 24 May 2017
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Chemistry (York)
Depositing User: Pure (York)
Date Deposited: 01 Feb 2019 10:20
Last Modified: 27 Dec 2024 00:12
Published Version: https://doi.org/10.1038/s41598-017-05042-4
Status: Published
Refereed: Yes
Identification Number: 10.1038/s41598-017-05042-4
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Filename: s41598_017_05042_4.pdf

Description: s41598-017-05042-4

Licence: CC-BY 2.5

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